PCB Design of mixed signal Board

Hi, I am designing a PCB which consist of Instrumentation Amplifiers, Programmable Gain Amplifiers, Switched Cap Filters, FPGAs & many ADCs. Involves low level Analog signals. How to patrician the layout so Analog & Digital signals do not interfere. The problem is the devices are low level Analog ICs, a lot of ADCs & Digital ICs. Can u advise ?

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