Universitat de Barcelona

University of Barcelona is a public university located in the city of Barcelona, Catalonia in Spain. With 63,000 students, it is one of the biggest universities in Spain. It is one of the oldest universities in Catalonia, establis

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1 technical article »

Non‑Invasive Monitoring Of Ph And Oxygen Using Miniaturized Electrochemical Sensors In An Animal Model Of Acute Hypoxia

Jan 19, 2022 | Laura Pla, Sergio Berdún, Mònica Mir, Lourders Rivas, Sandrine Miserere, Samuel Dulay, Josep Samitier, Elisenda Eixarch, Miriam Illa, and Eduard Gratacós

pH and oxygen electrochemical sensors were evaluated in a ventilatory hypoxia rabbit model. The ventilator hypoxia protocol included 3 differential phases: basal (100% FiO2), the hypoxia-acidosis period (10% FiO2) and recovery (100% FiO2). Sensors were tested in blood tissue (ex vivo sensing) and in muscular tissue (in vivo sensing). pH electrochemical and oxygen sensors were evaluated on the day of insertion (short-term evaluation) and pH electrochemical sensors were also tested after 5 days of insertion (long-term evaluation). pH and oxygen sensing were registered throughout the ventilatory hypoxia protocol (basal, hypoxia-acidosis, and recovery) and were compared with blood gas metabolites results from carotid artery catheterization (obtained with the EPOC blood analyzer)....

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